Because chronic kidney disease (CKD) is poorly inferred from serum creatinine alone, NKDEP strongly encourages clinical laboratories to routinely estimate and report GFR when serum creatinine is measured for patients 18 and older, when appropriate and feasible. Routinely reporting eGFR with all serum creatinine determinations allows laboratories to help identify reduced kidney function for providers, thus facilitate the detection of CKD. Routine reporting is easier for some laboratories than it is for others. The following information will help laboratories appropriately report eGFR.
Common problems. Below are considerations for addressing common issues laboratories face when reporting eGFR:
Reporting Values ≥ 60mL/min/1.73m2. NKDEP recommends reporting eGFR values greater than or equal to 60 mL/min/1.73 m2 simply as ≥ 60 mL/min/1.73 m2, and not as an exact number when using the MDRD Study equation. For values below 60 mL/min/1.73 m2, the report should give the numerical estimate rounded to a whole number (e.g., "32 mL/min/1.73 m2").
There are three reasons for this recommendation:
A laboratory that reports eGFR numeric values > 60 mL/min/1.73 m2 should consider using the CKD-EPI equation. Although the CKD-EPI equation is, on average, more accurate for values > 60 mL/min/1.73 m2 than is the MDRD Study equation, the influence of imprecision of creatinine assays on the uncertainty of an eGFR value is greater at higher eGFR values and should be considered when determining the highest eGFR value to report.
The following sample eGFR reports were developed using the Original MDRD Study equation:
Sample eGFR report for a 63-year-old woman
Sample eGFR report for a 63-year-old woman identified as African American
Sample eGFR report for a 62-year-old man
Sample eGFR report for a 55-year-old man
Note: If your printing system does not allow for superscripts, report the eGFR with mL/min/1.73 “square meters” or “m^2.”
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Page last updated: June 6, 2012