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U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Improving the understanding, detection, and management of kidney disease.

GFR MDRD Calculator for Adults (Conventional units)

In adults, the best equation for estimating glomerular filtration rate (GFR) from serum creatinine is the isotope dilution mass spectrometry (IDMS)-traceable Modification of Diet in Renal Disease (MDRD) Study equation1. All laboratories should be using creatinine methods calibrated to be IDMS traceable. Read more about creatinine standardization.

This IDMS-traceable MDRD study equation calculator is for use with Scr reported in mg/dL.

GFR (mL/min/1.73 m2) = 175 x (Scr)-1.154 x (Age)-0.203 x (0.742 if female) x (1.212 if African American) (conventional units)

The equation does not require weight because the results are reported normalized to 1.73 m2 body surface area, which is an accepted average adult surface area.

(mg/dL)
African American
Gender
mL/min/1.73 m2**

*This equation should only be used for patients 18 and older.

**The NKDEP presently recommends reporting estimated GFR values greater than or equal to 60 mL/min/1.73 m2 simply as "≥60 mL/min/1.73 m2", not an exact number.

References

1.Levey AS, Coresh J, Greene T, Stevens LA, Zhang YL, Hendriksen S, Kusek JW, Van Lente F; Chronic Kidney Disease Epidemiology Collaboration. Using standardized serum creatinine values in the modification of diet in renal disease study equation for estimating glomerular filtration rate.Ann Intern Med. 2006 Aug 15;145(4):247-54.

Page last updated: March 1, 2012