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U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Improving the understanding, detection, and management of kidney disease.

Laboratory tubes in a rack

Laboratory
Evaluation

Laboratory measurement and reporting are critical to promoting early detection and management of chronic kidney disease (CKD). NKDEP's major laboratory-related efforts address GFR, urine albumin, and cystatin C.

GFR »

NKDEP promotes routine reporting of estimated glomerular filtration rate (eGFR) with all serum creatinine determinations for patients age 18 and older, when appropriate and feasible. Automatic reporting by laboratories can help increase provider use of eGFR — a clinically important and practical tool for CKD detection and management. Learn more about estimating and reporting GFR.

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GFR Calculators »

NKDEP recommends the use of adult and pediatric GFR calculators to estimate kidney function for adults and children. Read more about GFR calculators to estimate kidney function for adults and children.

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Urine Albumin »

NKDEP and the IFCC established a joint work group to standardize measurement and reporting of urine albumin. This effort has the potential to redefine how CKD is diagnosed and managed.

NKDEP's Lab Working Group (LWG), a group of professionals representing various sectors of the clinical laboratory community, is largely responsible for conceiving and implementing these efforts. Learn more about NKDEP’s efforts in urine albumin and the efforts of the LWG.

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Update on Cystatin C »

Cystatin C is recognized as a useful marker for kidney damage. Several equations have been developed to estimate eGFR from serum cystatin C. Because cystatin C measurement procedures do not produce uniform results, the estimating equations are restricted for use only with results from the specific method used to develop them.

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Frequently Asked Questions »

Two key markers for CKD are urine albumin and estimated glomerular filtration rate (eGFR). Answer your questions about why and when to use these markers when evaluating patients for kidney disease.

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If you have questions about Laboratory Evaluation, write to csp@info.niddk.nih.gov.

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Page last updated: July 10, 2013