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U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Improving the understanding, detection, and management of kidney disease.

Centers for Disease Control and Prevention (CDC) Activities

Quality Improvement/Evidence of Therapy

This section describes current quality improvement and evidence of therapy programs of the Federal government related to chronic kidney disease.

Centers for Disease Control and Prevention (CDC)

CDC's CKD Health Evaluation Risk Information Sharing (CHERISH) is designed to test the feasibility of implementing a chronic kidney disease (CKD) detection/screening program in four states, to assess the degree of kidney disease in a high-risk population, to determine participant's subsequent access to care, and to address the likelihood of disease progression in those with evidence of CKD. This study is being conducted in collaboration with the National Kidney Foundation.

Contact Information
Desmond Williams, MD, PhD
CKD Initiative Team Lead, CDC Division of Diabetes Translation
Phone: 770-488-1158
Email: DEWilliams@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

CDC is promoting methicillin-resistant Staphylococcus aureus (MRSA) and S. aureus bloodstream infections (BSI) surveillance and prevention among hemodialysis facilities. This project will be conducted as part of a larger prevention collaborative involving a group of hospitals that are currently using a Positive Deviance Model as a behavior-based social change approach to eliminating healthcare-associated MRSA. In addition to examining the impact within the acute healthcare facilities where Positive Deviance is being applied, CDC will assess the impact on MRSA infection in outpatient dialysis centers that share patients with participating acute healthcare facilities.

Contact Information
Priti Patel, MD, MPH
CDC Division of Healthcare Quality Promotion
Phone: 404-639-4273
Email: PPatel@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

CDC, in collaboration with the Veterans Affairs - Puget Sound Health Care System, will examine the natural history of chronic kidney disease (CKD) and evaluate the rate of progression through the stages of CKD and development of complications.

Contact Information
Meda Pavkov, MD, PhD
Phone: 770-488-1160
Email: MPavkov@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

CDC's Cost-Effectiveness Study is using a lifetime simulation model to assess the costs and benefits of various interventions. The purpose of this project is to investigate the cost-effectiveness of interventions to prevent, delay, and treat CKD and its complications, and to develop a model that will not only help predict the progression of CKD, but will also test the effectiveness of various public health interventions.

CDC is researching the cost of illness through its Cost of Illness Study to document the direct and indirect costs of CKD and other diseases/conditions.

Contact Information
Desmond Williams, MD, PhD
CKD Initiative Team Lead, CDC Division of Diabetes Translation
Phone: 770-488-1158
Email: DEWilliams@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

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Scientific Research

This section describes basic and clinical research activities supported or sponsored by the Federal government.

Centers for Disease Control and Prevention (CDC)

CDC is working to determine the loss of albumin due to adsorption on the walls of urine collection containers and the sample cups used on analytical instrumentation. Containers from different vendors, different container materials, and various surface conditions will be evaluated using urine spiked with albumin. CDC will evaluate biological variability of urine albumin observed in a 24-hour urine collection, a timed overnight collection, and first and second morning collections. The findings from this work will be validated by measuring real patient samples to determine urinary albumin loss under optimal collection conditions. Patients representing different ethnicities with increased urinary protein will be identified and sampled. CDC will also try to determine the impact on albumin testing following multiple freeze/thaw cycles.

Contact Information
Gary Myers, PhD, FACB
Chief, CDC Clinical Chemistry Branch
Phone: 770-488-4606
Email: GMyers@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

CDC's Supplement Health, Aging, and Body Composition Study characterizes the extent of change in body composition in older men and women and identifies clinical conditions accelerating these changes. Additionally, it examines the health impact of these changes on strength, endurance, disability, and weight-related diseases of old age. The study targets people aged 70 years or older at high risk of developing chronic kidney disease.

Contact Information
Meda Pavkov, MD, PhD
Phone: 770-488-1160
Email: MPavkov@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

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Professional Education & Outreach

This section describes education and outreach to health professionals of the Federal government related to chronic kidney disease.

Centers for Disease Control and Prevention (CDC)

The Kidney Disease Initiative is designed to provide public health strategies for promoting kidney health. To help accomplish this goal, CDC convened a consensus conference of kidney disease experts and other stakeholders to establish priorities and strategies in the public health approach to kidney disease prevention and control. For example, CDC hosted a conference in March 2007 to discuss comprehensive public health strategies for preventing the development and progression of chronic kidney disease (CKD). Attendees included representatives from the U.S. Department of Health and Human Service agencies, universities, private and public institutions, and national organizations. The meeting summary with recommendations and the proceedings were published in the March 2009 issue and supplement of the American Journal of Kidney Disease.

CDC published articles related to CKD in the United States in its Morbidity and Mortality Weekly Report.

Contact Information
Nilka Rios Burrows, MT, MPH
Epidemiologist, CDC Division of Diabetes Translation
Phone: 770-488-1057
Email: NBurrows@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

The National Chronic Kidney Disease Fact Sheet 2010 provides information on prevalence, health consequences and resources on chronic kidney disease. The fact sheet provides statistics on CKD and kidney failure by age, sex and race/ethnicity, and offers information on risk factors and treatment.

The factsheet is a collaborative effort of CDC, other federal agencies, universities and nonprofit organizations that provide information for the public, kidney advocates and researchers. The fact sheet is not subject to copyright restrictions, and can be duplicated, adapted and distributed freely.

For more information on the chronic kidney disease initiative and to view the fact sheet, please visit http://www.cdc.gov/diabetes/pubs/pdf/kidney_Factsheet.pdf pdf icon (252K)

Contact Information
Sharon Saydah, PhD
LCDR USPHS
Senior Scientist, CDC, Division of Diabetes Translation
Phone: 301-458-4183
Email: SSaydah@cdc.gov
Web: http://www.cdc.gov/diabetes/pubs/pdf/kidney_Factsheet.pdf pdf icon (252K)

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Surveillance

This section describes surveillance activities and programs of the Federal government related to chronic kidney disease.

Centers for Disease Control and Prevention (CDC)

In collaboration with the Johns Hopkins University and the University of Michigan, CDC is working to establish a national surveillance system for chronic kidney disease (CKD). Its purpose is to identify existing local and national sources of CKD data; identify gaps and deficiencies in the existing data sources; and propose creative solutions to fill the gaps and remedy the deficiencies. The project will then examine the need for creating new data sources related to CKD and develop a plan to integrate all data sources into a functional surveillance system. CDC will carry out a feasibility study of the plan for the surveillance system, pilot test of the surveillance system, and deliver a final report to the CDC with recommendations.

CDC is also providing supplementary funding to the National Health and Nutrition Examination Survey for the collection and analysis of a laboratory specimen for creatinine and albumin. In the next survey cycle, the program will be pilot testing the collection of a second urine specimen for albumin analysis. The second specimen will be collected by the study participants in his/her home and mailed to the laboratory for analysis. The National Center for Health Statistics will direct the data collection contractor in establishing and revising protocols for the nephrology component and in preparing training and field manuals.

Contact Information
Desmond Williams, MD, PhD
CKD Initiative Team Lead, CDC Division of Diabetes Translation
Phone: 770-488-1158
Email: DEWilliams@cdc.gov
Web: http://www.cdc.gov/diabetes/projects/kidney.htm

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Page last updated: March 1, 2012