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U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES

Improving the understanding, detection, and management of kidney disease.

Centers for Disease Control and Prevention (CDC) Activities

Quality Improvement/Evidence of Therapy

This section describes current quality improvement and evidence of therapy programs of the Federal government related to chronic kidney disease.

Centers for Disease Control and Prevention (CDC)

CDC's CKD Health Evaluation Risk Information Sharing (CHERISH) is designed to test the feasibility of implementing a chronic kidney disease (CKD) screening and detection program in four states to assess the degree of kidney disease in a high-risk population, to determine the participant's subsequent access to care, and to address the likelihood of disease progression in those with evidence of CKD. This study is being conducted in collaboration with the National Kidney Foundation.

Contact Information
Desmond Williams, MD, PhD
CKD Initiative Team Lead
CDC Division of Diabetes Translation
Phone: 770-488-1158
Email: DEWilliams@cdc.gov
Web: http://www.cdc.gov/ckd

CDC is conducting bloodstream infection (BSI) surveillance and promoting BSI prevention among hemodialysis facilities. The CDC Dialysis BSI Prevention Collaborative is a partnership of freestanding and hospital-based outpatient dialysis facilities across the country aimed at preventing BSIs in hemodialysis patients. CDC provides evidence-based prevention guidelines and access to the National Healthcare Safety Network, a surveillance system that allows facilities to track infections. Also, CDC has developed for both patients and providers educational tools and materials  to prevent dialysis-associated infections.

Contact Information
Priti Patel, MD, MPH
CDC Division of Healthcare Quality Promotion
Phone: 404-639-4273
Email: PPatel@cdc.gov
Web: http://www.cdc.gov/ckd
http://www.cdc.gov/dialysis

CDC, in collaboration with the Veterans Affairs - Puget Sound Health Care System, is using chronic kidney disease (CKD) progression models to evaluate the natural history of the disease by estimating the rate of progression through the stages of CKD and development of complications. These models are constantly updated and validated.

Contact Information
Meda Pavkov, MD, PhD
Phone: 770-488-1160
Email: MPavkov@cdc.gov
Web: http://www.cdc.gov/ckd

CDC's Cost-Effectiveness Study is using a lifetime simulation model to assess the costs and benefits of various interventions to prevent, delay, and treat chronic kidney disease (CKD) and its complications. The goal is to develop a model that will not only help predict the progression of CKD, but will also test the long-term effectiveness of various public health interventions, and thus ultimately help achieve an efficient use of public health resources to prevent and control CKD.

CDC is also researching the cost of illness through its Cost-of-Illness Study to document the direct and indirect costs of CKD and other diseases or conditions.

Contact Information
Desmond Williams, MD, PhD
CKD Initiative Team Lead
CDC Division of Diabetes Translation
Phone: 770-488-1158
Email: DEWilliams@cdc.gov
Web: http://www.cdc.gov/ckd

Last Updated: June 1, 2014

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Scientific Research

This section describes basic and clinical research activities supported or sponsored by the Federal government.

Centers for Disease Control and Prevention (CDC)

CDC conducts numerous epidemiologic studies   to determine risk factors for incidence and progression of chronic kidney disease (CKD) and intramural research on the burden of CKD in the general and in special populations (e.g., mortality among people with CKD and incidence of kidney failure among people with diabetes, among other topics).

CDC is working to determine the loss of albumin due to adsorption on the walls of urine collection containers and the sample cups used on analytical instrumentation. Different container materials from different vendors and various surface conditions are evaluated using urine spiked with albumin. CDC is evaluating and comparing biological variability of urine albumin in 24-hour urine collections, timed overnight collections, and first and second morning collections in the general U.S. population. Persons representing different race/ethnicity groups with increased urinary albumin excretion will be identified and sampled. CDC will also determine the impact of multiple freeze and thaw cycles on urinary albumin concentration.

Contact Information
Sharon Saydah, PhD
CDR USPHS
Senior Scientist
CDC Division of Diabetes Translation
Phone: 301-458-4183
Email: SSaydah@cdc.gov
Web: http://www.cdc.gov/ckd

Last Updated: June 1, 2014

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Professional Education & Outreach

This section describes education and outreach to health professionals of the Federal government related to chronic kidney disease.

Centers for Disease Control and Prevention (CDC)

The Chronic Kidney Disease (CKD) Initiative is designed to provide public health strategies for promoting kidney health. To help accomplish this goal, CDC convened a consensus conference of kidney disease experts and other stakeholders to establish priorities and strategies in the public health approach to kidney disease prevention and control. Attendees included representatives from the U.S. Department of Health and Human Service agencies, universities, private and public institutions, and national organizations. The meeting summary with recommendations and the proceedings were published in the March 2009 issue and supplement of the American Journal of Kidney Diseases.

CDC has published articles related to CKD   in the United States in its Morbidity and Mortality Weekly Report and in peer review journals.

Contact Information
Nilka Ríos Burrows, MPH, MT (ASCP)
Epidemiologist
CDC Division of Diabetes Translation
Phone: 770-488-1057
Email: NBurrows@cdc.gov
Web: http://www.cdc.gov/ckd

The National Chronic Kidney Disease Fact Sheet 2014 pdf   provides information on prevalence, health consequences and resources on chronic kidney disease (CKD). The fact sheet provides statistics on CKD and kidney failure by age, sex and race/ethnicity, and offers information on risk factors and treatment.

The fact sheet is a collaborative effort of CDC, other federal agencies, universities, and nonprofit organizations that provide information for the public, kidney advocates, and researchers. The fact sheet is not subject to copyright restrictions and can be duplicated, adapted, and distributed freely.

Contact Information
Sharon Saydah, PhD
CDR USPHS
Senior Scientist
CDC Division of Diabetes Translation
Phone: 301-458-4183
Email: SSaydah@cdc.gov
Web: http://www.cdc.gov/diabetes/pubs/pdf/kidney_Factsheet.pdf pdf

Last Updated: June 1, 2014

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Surveillance

This section describes surveillance activities and programs of the Federal government related to chronic kidney disease.

Centers for Disease Control and Prevention (CDC)

In collaboration with the University of California at San Francisco and the University of Michigan, CDC implemented a national surveillance system for chronic kidney disease (CKD). The national CKD Surveillance System , available through an interactive Web site, documents the burden of CKD and its risk factors in the U.S. population over time and tracks the progress of our efforts to prevent, detect, and manage CKD. It also provides the means for evaluating, monitoring, and implementing quality improvement efforts by both federal and nonfederal agencies, and for monitoring kidney disease objectives for Healthy People 2020 . CDC and its partners continue to identify existing local, state, and national sources of CKD data; identify gaps and deficiencies in the existing data sources; and propose creative solutions to fill the gaps and remedy the deficiencies. The project team developed a plan to integrate all data sources into the CKD Surveillance System and examines the need for creating new data sources related to CKD.

CDC is also providing supplementary funding to the National Health and Nutrition Examination Survey for the collection and analysis of a laboratory specimen for creatinine and albumin. CDC’s National Center for Health Statistics directs the data collection contractor in establishing and revising protocols for the nephrology component of the survey and in preparing training and field manuals.

Contact Information
Desmond Williams, MD, PhD
CKD Initiative Team Lead
CDC Division of Diabetes Translation
Phone: 770-488-1158
Email: DEWilliams@cdc.gov
Web: http://www.cdc.gov/ckd

For more information about CDC’s CKD Initiative, please visit http://www.cdc.gov/diabetes/projects/pdfs/ckd_summary.pdf

Last Updated: June 1, 2014

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This information was reviewed by KICC agency representatives. It may not reflect new or future agency activities. For more information, please contact the listed representatives.

Page last updated: June 4, 2014